About 3,000 of our samples have been typed as part of the Wellcome Trust Case Control Consortium 2 , and these are being used in projects aimed at discovering genes behind a number of common diseases.

The basic idea is that a group of patients are typed at about one million genetic markers across the genome and these are then compared to non-patient samples.

Genetic markers that are found more often in the patients are likely to be associated with that disease. To check that the results are true, a second set of patients and non-patients are typed. If the association is replicated, then that is good news.

Our samples form the set of non-patients used in these replication studies. A number of papers using our samples, both by the WTCCC and other collaborators, have been published.